Article
Molecular determinants of hepatitis B and D virus entry restriction in mouse sodium taurocholate cotransporting polypeptide.
Journal of virology - 1 Jul 2013
Yan Huan, Peng Bo, He Wenhui, Zhong Guocai, Qi Yonghe, Ren Bijie, Gao Zhenchao, Jing Zhiyi, Song Mei, Xu Guangwei, Sui Jianhua, Li Wenhui
Abstract excerpt
Human hepatitis B virus (HBV) and its satellite virus, hepatitis D virus (HDV), primarily infect humans, chimpanzees, or tree shrews (Tupaia belangeri). Viral infections in other species are known to be mainly restricted at the entry level since viral replication can be achieved in the cells by transfection of the viral genome. Sodium taurocholate cotransporting polypeptide (NTCP) is a functional receptor for HBV...
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