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Article

Beta-adrenergic modulation of arrhythmogenesis and identification of targeted sites of antiarrhythmic therapy in Timothy (LQT8) syndrome: a theoretical study.

American journal of physiology. Heart and circulatory physiology - 1 Jan 2010

Sung Ruey J, Wu Yung-Han, Lai Nathan Hsing-Jung, Teng Chun-Hao, Luo Ching-Hsing, Tien Hui-Chun, Lo Chu-Pin, Wu Sheng-Nan

Abstract excerpt

Timothy syndrome (TS) is a malignant form of congenital long QT syndrome with a mode of arrhythmia onset often triggered by enhanced sympathetic tone. We sought to explore mechanisms by which beta-adrenergic stimulation (BAS) modulates arrhythmogenesis and to identify potential targeted sites of...

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Share to Anti-Arrhythmia Agents
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Calcium Channels, L-Type

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Share to Receptors, Adrenergic, beta

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Source

Identifiers

PMID: 19855067
DOI: 10.1152/ajpheart.00232.2009

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-19855067-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

Related research

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Beta-adrenergic modulation of arrhythmogenesis and identification of targeted sites of antiarrhythmic therapy in Timothy (LQT8) syndrome: a theoretical study.PMID 19855067Read ↗

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