Article

Probing cellular arrhythmogenesis using the O’Hara-Rudy model of the undiseased human ventricular cardiomyocyte

2020-11-16

Abstract excerpt

The ventricular action potential (AP) is subserved by an interdependent system of voltage-gated ion channels and pumps that both alter and respond (directly or indirectly) to the dynamic transmembrane potential (Δ ψ m ( t )) via voltage-dependent state transitions governing inward and outward ion currents. The native dynamic inward-outward current balance is subject to disruption caused by acquired or inherited...

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Literature Corpus work: 3b9eb115-84c3-5018-b193-061a67367769
DOI: 10.1101/2020.11.15.384032

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