Article
Enhancer of zeste 2 polycomb repressive complex 2 subunit polymorphisms in melanoma skin cancer risk.
Experimental dermatology - 1 Oct 2020
Belpinati Francesca, Malerba Giovanni, Dal Toè Melissa, Ceccuzzi Laura, Rodolfo Monica, Poli Albino, Turco Alberto, Vergani Elisabetta, Sangalli Antonella, Gomez-Lira Macarena
Abstract excerpt
Melanoma is the most deadly skin cancer, and its incidence is growing. EZH2, a member of the Polycomb Group (PcGs) proteins family, plays an important biological role in the occurrence and development of melanoma. EZH2 germline genetic polymorphisms have not been yet evaluated in melanoma predisposition. Three hundred thirty sporadic Italian melanoma patients and 333 healthy volunteers were genotyped to analyse...
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