Article
Tissue plasminogen activator and plasminogen activator inhibitor type 1 gene polymorphism in patients with gastric ulcer complicated with bleeding.
Journal of Korean medical science - 1 Feb 2003
Kim Hong-Soo, Hwang Kyu-Yoon, Chung Il-Kwon, Park Sang-Heum, Lee Moon-Ho, Kim Sun-Joo, Hong Sae-Yong
Abstract excerpt
Tissue plasminogen activator (t-PA) and plasminogen activator inhibitor type 1 (PAI-1) may be involved in the pathogenesis of peptic ulcers through suppression of fibrinolysis. This study was designed to investigate associations of t-PA and PAI-1 genes with clinical features of the patients with bleeding gastric ulcers. Eighty-four patients with peptic ulcers and 100 controls were studied between January 1998 and...
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