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Article

Association of DNA repair polymorphisms with DNA repair functional outcomes in healthy human subjects.

Carcinogenesis - 1 Mar 2007

Vodicka Pavel, Stetina Rudolf, Polakova Veronika, Tulupova Elena, Naccarati Alessio, Vodickova Ludmila, Kumar Rajiv, Hanova Monika, Pardini Barbara, Slyskova Jana, Musak Ludovit, De Palma Giuseppe, Soucek Pavel, Hemminki Kari

Abstract excerpt

We investigated association between polymorphisms in DNA repair genes and the capacity to repair DNA damage induced by gamma-irradiation and by base oxidation in a healthy population. Irradiation-specific DNA repair rates were significantly decreased in individuals with XRCC1 Arg399Gln homozygous...

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Source

Identifiers

PMID: 17028303
DOI: 10.1093/carcin/bgl187

Genes

XRCC1
SSB

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-17028303-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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