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Article

Dysregulation of miR-185, miR-193a, and miR-450a in the skin are linked to the depressive phenotype.

Progress in neuro-psychopharmacology & biological psychiatry - 10 Jan 2021

Kaadt Erik, Højgaard Kristoffer, Mumm Birgitte, Christiansen Sofie Laage, Müller Heidi Kaastrup, Damgaard Christian Kroun, Elfving Betina

Abstract excerpt

BACKGROUND: Dysregulated microRNAs (miRNAs) in dermal fibroblasts of depressive subjects, indicate biomarker potential and can possibly aid clinical diagnostics. To overcome methodological challenges related to human experiments and fibroblast cultures, we here validate 38 miRNAs previously observed to be dysregulated in human fibroblasts from depressed subjects, in the skin of four distinct rat models of...

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PMID: 32738353
DOI: 10.1016/j.pnpbp.2020.110052

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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