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Article

Pathogenetic and therapeutic applications of microRNAs in major depressive disorder.

Progress in neuro-psychopharmacology & biological psychiatry - 4 Jan 2016

Dwivedi Yogesh

Abstract excerpt

As a class of noncoding RNAs, microRNAs (miRNAs) regulate gene expression by inhibiting translation of messenger RNAs. These miRNAs have been shown to play a critical role in higher brain functioning and actively participate in synaptic plasticity. Pre-clinical evidence demonstrates that expression of miRNAs is differentially altered during stress. On the other hand, depressed individuals show marked changes in...

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Identifiers

PMID: 25689819
DOI: 10.1016/j.pnpbp.2015.02.003
PMCID: PMC4537399

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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