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Article

Identification of relevant genetic alterations in cancer using topological data analysis.

Nature communications - 30 Jul 2020

Rabadán Raúl, Mohamedi Yamina, Rubin Udi, Chu Tim, Alghalith Adam N, Elliott Oliver, Arnés Luis, Cal Santiago, Obaya Álvaro J, Levine Arnold J, Cámara Pablo G

Abstract excerpt

Large-scale cancer genomic studies enable the systematic identification of mutations that lead to the genesis and progression of tumors, uncovering the underlying molecular mechanisms and potential therapies. While some such mutations are recurrently found in many tumors, many others exist solely within a few samples, precluding detection by conventional recurrence-based statistical approaches. Integrated...

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Identifiers

PMID: 32732999
DOI: 10.1038/s41467-020-17659-7
PMCID: PMC7393176

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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