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Article

A scalable method for molecular network reconstruction identifies properties of targets and mutations in acute myeloid leukemia.

Journal of computational biology : a journal of computational molecular cell biology - 1 Apr 2015

Ong Edison, Szedlak Anthony, Kang Yunyi, Smith Peyton, Smith Nicholas, McBride Madison, Finlay Darren, Vuori Kristiina, Mason James, Ball Edward D, Piermarocchi Carlo, Paternostro Giovanni

Abstract excerpt

A key aim of systems biology is the reconstruction of molecular networks. We do not yet, however, have networks that integrate information from all datasets available for a particular clinical condition. This is in part due to the limited scalability, in terms of required computational time and p...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 25844667
DOI: 10.1089/cmb.2014.0297
PMCID: PMC4394180

Genes

CDK1
CDK2
CDK4
CDK6

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-25844667-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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