Article
Role of enterocyte-specific gene polymorphisms in response to adjuvant treatment for stage III colorectal cancer.
Pharmacogenetics and genomics - 1 Jan 2021
Suenaga Mitsukuni, Cao Shu, Zhang Wu, Matsusaka Satoshi, Okazaki Satoshi, Berger Martin D, Miyamoto Yuji, Schirripa Marta, Barzi Afsaneh, Yamamoto Noriko, Yamaguchi Toshiharu, Lenz Heinz-Josef
Abstract excerpt
OBJECTIVES: The enterocyte subtype of colorectal cancer (CRC) responds favorably to oxaliplatin-based adjuvant treatment for stage III CRC. We examined the clinical significance of single-nucleotide polymorphisms (SNPs) in enterocyte-related genes MS4A12 and CDX2 in response to adjuvant treatment for stage III CRC. PATIENTS AND METHODS: A total of 350 patients with stage III CRC were included: 274 received...
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