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Article

Association of XPD Asp312Asn polymorphism and response to oxaliplatin-based first-line chemotherapy and survival in patients with metastatic colorectal cancer.

Advances in clinical and experimental medicine : official organ Wroclaw Medical University - 1 Nov 2019

Liu Zhuo, Kong Jiangyin, Kong Yuanyuan, Cai Feng, Xu Xiaocheng, Liu Jun, Wang Shihua

Abstract excerpt

BACKGROUND: Identification of biomarkers predicting a response to chemotherapeutic drugs would greatly ease the selection of personalized therapy. The protein xeroderma pigmentosum group D (XPD) functions in nucleotide excision repair (NER) to remove DNA cross-links and in the regulation of transcription. The potential role of the Asp312Asn polymorphism in predicting the response to chemotherapy has not been...

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PMID: 31756062
DOI: 10.17219/acem/108552

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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