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Article

Identification of a subpopulation of long-term tumor-initiating cells in colon cancer.

Bioscience reports - 28 Aug 2020

Peng Linglong, Xiong Yongfu, Wang Rong, Xiang Ling, Zhou He, Gu Haitao

Abstract excerpt

Long-term tumor-initiating cells (LT-TICs) are viewed as a quantifiable target for colon cancer therapy owing to their extensive self-renewal and tumorigenic and metastatic capacities. However, it is unknown which subpopulation of colon cancer cells contains LT-TICs. Here, based on the methods for isolating and identifying cancer stem cells (CSCs) and the functional features of LT-TICs, we aimed to identify a...

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Identifiers

PMID: 32729895
DOI: 10.1042/BSR20200437
PMCID: PMC7447854

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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