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Article

Cancer stemness contributes to cluster formation of colon cancer cells and high metastatic potentials.

Clinical and experimental pharmacology & physiology - 1 May 2020

Kapeleris Joanna, Zou Hong, Qi Yan, Gu Yushu, Li Jingyun, Schoning Jennifer, Monteiro Michael J, Gu Wenyi

Abstract excerpt

The ability of cancer cells to form clusters is a characteristic feature in the development of metastatic tumours with drug resistance. Several studies demonstrated that clusters of circulating tumour cells (CTCs) have a greater metastatic potential to establish new tumours at secondary sites than single CTCs. However, the mechanism of cluster formation is not well understood. In this study, we investigated...

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Identifiers

PMID: 31883392
DOI: 10.1111/1440-1681.13247

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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