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The SW480 cell line as a model of resident and migrating colon cancer stem cells

5 Aug 2024

Abstract excerpt

Intra-tumor heterogeneity, i.e., the presence of diverse cell types and subpopulations within tumors, presents a significant obstacle in cancer treatment due to its negative consequences for resistance to therapy and disease recurrence. However, the mechanisms that underlie intra-tumor heterogeneity and result in the plethora of different cancer cells within a single lesion remain poorly understood. Here, we...

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Cancer Cells and Metastasis
Cancer Genomics and Diagnostics
Single-cell and spatial transcriptomics

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 39246444
DOI: 10.1016/j.isci.2024.110658

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