Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Topics Community

Article

Wnt/β-catenin Signaling Inhibitors suppress the Tumor-initiating properties of a CD44+CD133+ subpopulation of Caco-2 cells

1 Jan 2021

Abstract excerpt

Tumor-initiating cells or cancer stem cells are a subset of cancer cells that have tumorigenic potential in human cancer. Although several markers have been proposed to distinguish tumor-initiating cells from colorectal cancer cells, little is known about how this subpopulation contributes to tumorigenesis. Here, we characterized a tumor-initiating cell subpopulation from Caco-2 colorectal cancer cells. Based on...

Source

Identifiers

PMID: 33994850
DOI: 10.7150/ijbs.58612

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

0

discussions

0

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Wnt/β-catenin Signaling Inhibitors suppress the Tumor-initiating properties of a CD44+CD133+ subpopulation of Caco-2 cellsPMID 33994850Read ↗

Isolation and propagation of a human CD133(-) colon tumor-derived cell line with tumorigenic and angiogenic properties.Semantic proximity Read ↗

CD133 as a target for colon cancerSemantic proximity Read ↗

Identification of a subpopulation of long-term tumor-initiating cells in colon cancer.Semantic proximity Read ↗

Characteristics of CD133 <sup>+</sup> Human Colon Cancer SW620 CellsSemantic proximity Read ↗

Tumor-Initiating Cells: a criTICal review of isolation approaches and new challenges in targeting strategiesSemantic proximity Read ↗

CD133 expression is not restricted to stem cells, and both CD133+ and CD133- metastatic colon cancer cells initiate tumors.Semantic proximity Read ↗

Establishment of Highly Tumorigenic Human Colorectal Cancer Cell Line (CR4) with Properties of Putative Cancer Stem CellsSemantic proximity Read ↗

Cancer stem cells from colorectal cancer-derived cell linesSemantic proximity Read ↗

Selective AKT Inhibition by MK-2206 Represses Colorectal Cancer-Initiating Stem CellsSemantic proximity Read ↗

Colorectal Cancer Stem CellsSemantic proximity Read ↗

Single-cell cloning of colon cancer stem cells reveals a multi-lineage differentiation capacitySemantic proximity Read ↗

Deciphering biological characteristics of tumorigenic subpopulations in human colorectal cancer reveals cellular plasticitySemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.