Article
Identification of novel mutations of TP53, ALK and RET gene in metastatic thymic squamous cell carcinoma and its therapeutic implication.
Lung cancer (Amsterdam, Netherlands) - 1 Jul 2013
Hu Zhenli, Wang Jinghan, Yao Tony, Hong Ruey-Long, Zhang Keqiang, Gao Hanlin, Wu Xiwei, Li Jie, Bai Chong, Yen Yun
Abstract excerpt
Thymic tumors are epithelial tumors of the thymus for which multimodal therapies are often ineffective because of a lack of standardized regimens. Due to the low incidence, the molecular pathology and genomic abnormalities of thymic epithelial tumors are largely unknown. In this study, we report our comprehensively genomic study on a case of metastatic thymic tumor. Using next generation deep DNA sequencing...
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