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Article

Kynurenine pathway is altered in BDNF Val66Met knock-in mice: Effect of physical exercise.

Brain, behavior, and immunity - 1 Oct 2020

Ieraci Alessandro, Beggiato Sarah, Ferraro Luca, Barbieri Silvia S, Popoli Maurizio

Abstract excerpt

The Brain-Derived Neurotrophic Factor (BDNF) Val66Met polymorphism has been correlated with increased predisposition to develop cognitive and psychiatric disorders, and with a reduced response to some therapeutic treatments. However, the mechanisms underlying these impairments are currently not completely understood. Remarkably, kynurenine pathway alterations have also been implicated in cognitive and psychiatric...

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PMID: 32726686
DOI: 10.1016/j.bbi.2020.07.031

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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