Article
Impact of HLA allele mismatch at HLA-A, -B, -C, -DRB1, and -DQB1 on outcomes in haploidentical stem cell transplantation.
Bone marrow transplantation - 1 May 2018
Huo Ming-Rui, Pei Xu-Ying, Li Dan, Chang Ying-Jun, Xu Lan-Ping, Zhang Xiao-Hui, Liu Kai-Yan, Huang Xiao-Jun
Abstract excerpt
The impact of human leukocyte antigen (HLA) allele mismatch on transplant outcomes in haploidentical stem cell transplantation (haplo-SCT) has not been established. We retrospectively studied 595 patients with hematologic malignancy who received haplo-SCT. The impact of multiple HLA allele mismatches (HLA-A, -B, -C, -DRB1, and -DQB1) and each HLA allele mismatch on transplant outcomes was analyzed. Greater number...
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