Article
Pathway-Affecting Single Nucleotide Polymorphisms (SNPs) in RPS6KA1 and MBIP Genes are Associated with Breast Cancer Risk.
Asian Pacific journal of cancer prevention : APJCP - 1 Jul 2020
Shareefi Ghadah, Turkistani Alaa Nabil, Alsayyah Ahmed, Kussaibi Haitham, Abdel Hadi Maha, Alkharsah Khaled R
Abstract excerpt
BACKGROUND: Genetic mutations and polymorphisms play an important role in the transformation of primary cells to malignant cells as it may lead to disturbance of vital pathways regulating cell cycle, DNA damage repair, and apoptosis. In this study, we genotyped single nucleotide polymorphisms (SNPs) which were predicted to affect certain pathways and to increase the risk of breast cancer. METHODS: The study...
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