Article
Association of single nucleotide polymorphisms in FGF-RAS/MAP signalling cascade with breast cancer susceptibility.
General physiology and biophysics - 1 Dec 2017
Dankova Zuzana, Zubor Pavol, Grendar Marian, Kapinova Andrea, Zelinova Katarina, Jagelkova Mariana, Gondova Alexandra, Dokus Karol, Kalman Michal, Lasabova Zora, Danko Jan
Abstract excerpt
The fibroblast growth factor receptors (FGFRs) and Ras/mitogen activated protein (RAS/MAP) signalling cascades are the main molecular pathways involved in breast carcinogenesis. This study aims to determine the association between FGF10 (rs4415084 C>T), FGFR2 (rs2981582 C>T) and MAP3K1 (rs889312 A>C) gene polymorphisms and breast cancer, to analyse the discriminative ability of each SNP and to test the accuracy...
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