Article
The Secretome Analysis of Activated Human Renal Fibroblasts Revealed Beneficial Effect of the Modulation of the Secreted Peptidyl-Prolyl Cis-Trans Isomerase A in Kidney Fibrosis.
Cells - 18 Jul 2020
Dihazi Gry H, Eltoweissy Marwa, Jahn Olaf, Tampe Björn, Zeisberg Michael, Wülfrath Hauke S, Müller Gerhard A, Dihazi Hassan
Abstract excerpt
The secretome is an important mediator in the permanent process of reciprocity between cells and their environment. Components of secretome are involved in a large number of physiological mechanisms including differentiation, migration, and extracellular matrix modulation. Alteration in secretome composition may therefore trigger cell transformation, inflammation, and diseases. In the kidney, aberrant protein...
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