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Article

Cellular phenotypic transitions in diabetic nephropathy: An update

2 Nov 2022

Abstract excerpt

Diabetic nephropathy (DN) is a major cause of morbidity and mortality in diabetes and is the most common cause of end stage renal disease (ESRD). Renal fibrosis is the final pathological change in DN. It is widely believed that cellular phenotypic switching is the cause of renal fibrosis in diabetic nephropathy. Several types of kidney cells undergo activation and differentiation and become reprogrammed to...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 36408221
DOI: 10.3389/fphar.2022.1038073

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