Lethal mutations with fluctuating heterozygous effect: the lethal force of effective dominance.

Abstract excerpt

The theory of population genetics leads to the expectation that in very large populations the frequencies of recessive lethal mutations are close to the square root of the mutation rate, corresponding to mutation-selection balance. There are numerous examples where the frequencies of such alleles are orders of magnitude larger than this result. In this work we theoretically investigate the role of temporal...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Genes, Dominant
• Share to Genes, Lethal
• Share to Genes, Recessive