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Article

Molecular Diagnostics of Gliomas Using Next Generation Sequencing of a Glioma-Tailored Gene Panel.

Brain pathology (Zurich, Switzerland) - 1 Mar 2017

Zacher Angela, Kaulich Kerstin, Stepanow Stefanie, Wolter Marietta, Köhrer Karl, Felsberg Jörg, Malzkorn Bastian, Reifenberger Guido

Abstract excerpt

Current classification of gliomas is based on histological criteria according to the World Health Organization (WHO) classification of tumors of the central nervous system. Over the past years, characteristic genetic profiles have been identified in various glioma types. These can refine tumor diagnostics and provide important prognostic and predictive information. We report on the establishment and validation of...

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Identifiers

PMID: 26919320
DOI: 10.1111/bpa.12367
PMCID: PMC8029406

Genes

TERT
ATRX
CIC
EGFR
PTEN

Provenance

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