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Article

Mitochondrial haplotypes affect metabolic phenotypes in the Drosophila Genetic Reference Panel.

Nature metabolism - 1 Dec 2019

Bevers Roel P J, Litovchenko Maria, Kapopoulou Adamandia, Braman Virginie S, Robinson Matthew R, Auwerx Johan, Hollis Brian, Deplancke Bart

Abstract excerpt

The nature and extent of mitochondrial DNA variation in a population and how it affects traits is poorly understood. Here we resequence the mitochondrial genomes of 169 Drosophila Genetic Reference Panel lines, identifying 231 variants that stratify along 12 mitochondrial haplotypes. We identify 1,845 cases of mitonuclear allelic imbalances, thus implying that mitochondrial haplotypes are reflected in the nuclear...

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PMID: 32694676
DOI: 10.1038/s42255-019-0147-3

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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