Article
Multidimensional phenotyping predicts lifespan and quantifies health in Caenorhabditis elegans.
PLoS computational biology - 1 Jul 2020
Martineau Céline N, Brown André E X, Laurent Patrick
Abstract excerpt
Ageing affects a wide range of phenotypes at all scales, but an objective measure of ageing remains challenging, even in simple model organisms. To measure the ageing process, we characterized the sequence of alterations of multiple phenotypes at organismal scale. Hundreds of morphological, postural, and behavioral features were extracted from high-resolution videos. Out of the 1019 features extracted, 896 are...
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