Article
Identification by machine vision of the rate of motor activity decline as a lifespan predictor in C. elegans.
Neurobiology of aging - 1 Sept 2009
Hsu Ao-Lin, Feng Zhaoyang, Hsieh Meng-Yin, Xu X Z Shawn
Abstract excerpt
One challenge in aging research concerns identifying physiological parameters or biomarkers that can reflect the physical health of an animal and predict its lifespan. In C. elegans, a model organism widely used in aging research, motor deficits develop in old worms. Here we employed machine vision to quantify worm locomotion behavior throughout lifespan. We confirm that aging worms undergo a progressive decline...
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