Article
Assessing Health Span in Caenorhabditis elegans: Lessons From Short-Lived Mutants.
The journals of gerontology. Series A, Biological sciences and medical sciences - 1 Apr 2017
Rollins Jarod A, Howard Amber C, Dobbins Sarah K, Washburn Elsie H, Rogers Aric N
Abstract excerpt
Genetic changes resulting in increased life span are often positively associated with enhanced stress resistance and somatic maintenance. A recent study found that certain long-lived Caenorhabditis elegans mutants spent a decreased proportion of total life in a healthy state compared with controls, raising concerns about how the relationship between health and longevity is assessed. We evaluated seven markers of...
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