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Article

[Risk of Multiple Sclerosis: Analysis of Interactions Between Variants of Nuclear and Mitochondrial Genomes].

Molekuliarnaia biologiia - 1 Jan 2000

Kozin M S, Kiselev I S, Baulina N M, Pavlova G V, Boyko A N, Kulakova O G, Favorova O O

Abstract excerpt

There is increasing evidence that the interaction of the mitochondrial and nuclear genomes substantially affects the risk of neurodegenerative diseases. The role of mitonuclear interactions in the development of multiple sclerosis, a severe chronic neurodegenerative disease of a polygenic nature, is poorly understood. In this work, we analyzed the association of multiple sclerosis with two-component mitonuclear...

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PMID: 34837699
DOI: 10.31857/S0026898421060070

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