Article
Complex gene-gene interactions in multiple sclerosis: a multifactorial approach reveals associations with inflammatory genes.
Neurogenetics - 1 Jan 2007
Motsinger Alison A, Brassat David, Caillier Stacy J, Erlich Henry A, Walker Karen, Steiner Lori L, Barcellos Lisa F, Pericak-Vance Margaret A, Schmidt Silke, Gregory Simon, Hauser Stephen L, Haines Jonathan L, Oksenberg Jorge R, Ritchie Marylyn D
Abstract excerpt
The complex inheritance involved in multiple sclerosis (MS) risk has been extensively investigated, but our understanding of MS genetics remains rudimentary. In this study, we explore 51 single nucleotide polymorphisms (SNPs) in 36 candidate genes from the inflammatory pathway and test for gene-g...
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