Article
Epithelioid glioblastoma with microglia features: potential for novel therapy.
Brain pathology (Zurich, Switzerland) - 1 Nov 2020
Nakagomi Nami, Sakamoto Daisuke, Hirose Takanori, Takagi Toshinori, Murase Makiko, Nakagomi Takayuki, Yoshimura Shinichi, Hirota Seiichi
Abstract excerpt
Epithelioid glioblastoma (E-GBM) was recently designated as a subtype of glioblastoma (GBM) by the World Health Organization (2016). E-GBM is an aggressive and rare variant of GBM that primarily occurs in children and young adults. Although most characterized cases of E-GBM harbor a mutation of the BRAF gene in which valine (V) is substituted by glutamic acid (E) at amino acid 600 (BRAF-V600E), in addition to...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
