Article
CCN6 regulates mitochondrial respiratory complex assembly and activity.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology - 1 Sept 2020
Padhan Deepesh Kumar, Sengupta Archya, Patra Milan, Ganguly Ananya, Mahata Sushil Kumar, Sen Malini
Abstract excerpt
Cellular communication network factor 6 (CCN6) mutations are linked with Progressive Pseudo Rheumatoid Dysplasia (PPRD) a debilitating musculoskeletal disorder. The function of CCN6 and the mechanism of PPRD pathogenesis remain unclear. Accordingly, we focused on the functional characterization of CCN6 and CCN6 mutants. Using size exclusion chromatography and native polyacrylamide gel electrophoresis we...
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