Article
Genomic characterization of MICA gene using multiple next generation sequencing platforms: A validation study.
HLA - 1 Oct 2020
Zou Yizhou, Duke Jamie L, Ferriola Deborah, Luo Qizhi, Wasserman Jenna, Mosbruger Timothy L, Luo Weiguang, Cai Liang, Zou Kevin, Tairis Nikolaos, Damianos Georgios, Pagkrati Ioanna, Kukuruga Debra, Huang Yanping, Monos Dimitri S
Abstract excerpt
We have developed a protocol regarding the genomic characterization of the MICA gene by next generation sequencing (NGS). The amplicon includes the full length of the gene and is about 13 kb. A total of 156 samples were included in the study. Ninety-seven of these samples were previously characterized at MICA by legacy methods (Sanger or sequence specific oligonucleotide) and were used to evaluate the accuracy,...
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