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Article

Advances in MICA genotyping: characterization of 406 novel alleles and their frequencies in multiple populations.

Frontiers in immunology - 1 Jan 2026

Albrecht Viviane, Paech Christin, Putke Kathrin, Schöfl Gerhard, Sauter Jürgen, Schmidt Alexander H, Lange Vinzenz, Klussmeier Anja

Abstract excerpt

In 2020, we reported MICA allele frequencies from a cohort of over one million German individuals. This study identified MICA*008 (42%), MICA*002 (12%), and MICA*009 (9%) as the most common MICA alleles at protein resolution. Additionally, we discovered novel alleles with a cumulative frequency of 0.3%. To reduce this fraction of unnamed sequences, we aimed to fully characterize the most frequent novel alleles...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 41846934
DOI: 10.3389/fimmu.2026.1741611
PMCID: PMC12989365

Genes

MICA

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

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