The association of growth differentiation factor 5 rs143383 gene polymorphism with osteoarthritis: a systematic review and meta-analysis.

doi:10.1186/s13018-023-04245-y

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Article

The association of growth differentiation factor 5 rs143383 gene polymorphism with osteoarthritis: a systematic review and meta-analysis.

Journal of orthopaedic surgery and research - 10 Oct 2023

Wang Yue-Peng, Di Wen-Jia, Yang Su, Qin Shi-Lei, Xu Yun-Feng, Han Peng-Fei, Hou Ke-Dong

Abstract excerpt

BACKGROUND: Osteoarthritis (OA) is caused by a complex set of pathophysiological factors. The genetic factors involved in the occurrence and progress of the disease have been widely discussed by scholars. It was found that growth differentiation factor 5 (GDF5) gene polymorphisms may be linked to OA susceptibility, which has been controversial and needs to be further confirmed by an updated meta-analysis....

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PMID: 37817264
DOI: 10.1186/s13018-023-04245-y
PMCID: PMC10563324

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