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Article

Increased predominance of the matured ventricular subtype in embryonic stem cell-derived cardiomyocytes in vivo

17 Jul 2020

Abstract excerpt

Accumulating evidence suggests that human pluripotent stem cell-derived cardiomyocytes can affect "heart regeneration", replacing injured cardiac scar tissue with concomitant electrical integration. However, electrically coupled graft cardiomyocytes were found to innately induce transient post-transplant ventricular tachycardia in recent large animal model transplantation studies. We hypothesised that these...

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PMID: 32681032
DOI: 10.1038/s41598-020-68373-9

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