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Article

Overexpression of Kir2.1 channel in embryonic stem cell-derived cardiomyocytes attenuates posttransplantation proarrhythmic risk in myocardial infarction.

Heart rhythm - 1 Feb 2013

Liao Song-Yan, Tse Hung-Fat, Chan Yau-Chi, Mei-Chu Yip Pandora, Zhang Yuelin, Liu Yuan, Li Ronald A

Abstract excerpt

BACKGROUND: Cellular replacement strategies using embryonic stem cell-derived cardiomyocytes (ESC-CMs) have been shown to improve left ventricular (LV) ejection fraction and prevent LV remodeling post-myocardial infarction (MI). Nonetheless, the immature electrical phenotypes of ESC-CMs may increase the risk of ventricular tachyarrhythmias (VTs) and sudden death. OBJECTIVE: To investigate whether the forced...

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Identifiers

PMID: 23041574
DOI: 10.1016/j.hrthm.2012.10.008

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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