Biallelic mutations in CDC20 cause female infertility characterized by abnormalities in oocyte maturation and early embryonic development

Abstract excerpt

Dear Editor, Previously, the Mendelian phenotypes in human oocyte maturation arrest, fertilization failure and early embryonic arrest, are largely underestimated. In recent years, “missing” Mendelian phenotypes and genes in these processes are beginning to be uncovered by us and others (Huang et al., 2014; Alazami et al., 2015; Feng et al., 2016; Xu et al., 2016; Chen et al., 2017; Sang et al., 2019). However,...

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