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DLGAP5 mutations Disrupt Normal Chromosome Segregation and Spindle Formation of human Oocyte Meiosis and Lead to Female Infertility

22 May 2025

Abstract excerpt

Dear Editor, Nowadays, approximately one out of six couples of reproductive age are confronted with infertility. Assisted reproductive technology (ART) constitutes one of the most effective measures to address this issue; however, in certain instances, ART fails [1]. Moreover, some patients experience recurrent ART failure with a uniform phenotype, suggesting a genetic component to their condition [2]. Recently,...

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PMID: 40416599
DOI: 10.1002/mco2.70224

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