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Gene mutations impede oocyte maturation, fertilization, and early embryonic development.

BioEssays : news and reviews in molecular, cellular and developmental biology - 1 Oct 2022

Fei Cai-Feng, Zhou Li-Quan

Abstract excerpt

Reproductive diseases are a long-standing problem and have become more common in the world. Currently, 15% of the world's population suffers from infertility, and half of them are women. Maturation of oocytes, successful fertilization, and high-quality embryos are prerequisites for pregnancy. With the development of assisted reproductive technology and advanced genetic assays, we have found that infertility in...

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PMID: 35900055
DOI: 10.1002/bies.202200007

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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