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Article

Ranking essential bacterial processes by speed of mutant death.

Proceedings of the National Academy of Sciences of the United States of America - 28 Jul 2020

Gallagher Larry A, Bailey Jeannie, Manoil Colin

Abstract excerpt

Mutant phenotype analysis of bacteria has been revolutionized by genome-scale screening procedures, but essential genes have been left out of such studies because mutants are missing from the libraries analyzed. Since essential genes control the most fundamental processes of bacterial life, this is a glaring deficiency. To address this limitation, we developed a procedure for transposon insertion mutant...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Identifiers

PMID: 32665440
DOI: 10.1073/pnas.2001507117
PMCID: PMC7395459

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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