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Article

Ndrg1-deficient mice exhibit a progressive demyelinating disorder of peripheral nerves.

Molecular and cellular biology - 1 May 2004

Okuda Tomohiko, Higashi Yujiro, Kokame Koichi, Tanaka Chihiro, Kondoh Hisato, Miyata Toshiyuki

Abstract excerpt

NDRG1 is an intracellular protein that is induced under a number of stress and pathological conditions, and it is thought to be associated with cell growth and differentiation. Recently, human NDRG1 was identified as a gene responsible for hereditary motor and sensory neuropathy-Lom (classified as Charcot-Marie-Tooth disease type 4D), which is characterized by early-onset peripheral neuropathy, leading to severe...

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Identifiers

PMID: 15082788
DOI: 10.1128/MCB.24.9.3949-3956.2004
PMCID: PMC387740

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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