Keratinocyte-Derived Exosomes in Painful Diabetic Neuropathy

Abstract excerpt

<h4>ABSTRACT</h4> Painful diabetic neuropathy (PDN) is a challenging complication of diabetes with patients experiencing a painful and burning sensation in their extremities. Existing treatments provide limited relief without addressing the underlying mechanisms of the disease. PDN involves the gradual degeneration of nerve fibers in the skin. Keratinocytes, the most abundant epidermal cell type, are closely posi...

Topics

Open a Topic to create a Post that cites this publication.

• Advancements in Transdermal Drug Delivery
• Axon Guidance and Neuronal Signaling
• Cardiovascular Disease and Adiposity
• Corneal Surgery and Treatments
• Extracellular vesicles in disease
• MicroRNA in disease regulation
• Nerve injury and regeneration
• Pain Mechanisms and Treatments

Identifiers and source

Literature Corpus work

fb2661d2-f02b-5b4e-a35e-64ac4d125850

DOI

10.1101/2024.08.21.608803