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Article

MTHFR variants modify the association between pre-pregnancy BMI and postpartum abnormal glucose tolerance among women with gestational diabetes mellitus.

BMC endocrine disorders - 12 May 2026

Gu Chunming, Lai Kefeng, Liu Yan, Wu Weixiang, Zhang Xiaodan, Zhang Zhili, Mai Qiongdan, Zheng Xianhua, Luo Mingyong

Abstract excerpt

BACKGROUND: Methylenetetrahydrofolate reductase (MTHFR) gene polymorphisms and obesity are associated with glucose metabolism dysregulation. This study aimed to investigate the individual and joint effects of MTHFR gene polymorphisms and pre-pregnancy body mass index (pre-BMI) status on postpartum abnormal glucose tolerance (PAGT) risk among women with gestational diabetes mellitus (GDM). METHODS: This...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 42121155
DOI: 10.1186/s12902-026-02310-1
PMCID: PMC13335208

Genes

MTHFR

Variants

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

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