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Article

Functional and behavioral signatures of Kv7 activator drug subtypes.

Epilepsia - 1 Aug 2020

Kanyo Richard, Wang Caroline K, Locskai Laszlo F, Li Jingru, Allison W Ted, Kurata Harley T

Abstract excerpt

OBJECTIVE: Voltage-gated potassium channels of the KCNQ (Kv7) family are targeted by a variety of activator compounds with therapeutic potential for treatment of epilepsy. Exploration of this drug class has revealed a variety of effective compounds with diverse mechanisms. In this study, we aimed to clarify functional criteria for categorization of Kv7 activator compounds, and to compare the effects of...

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Identifiers

PMID: 32652600
DOI: 10.1111/epi.16592

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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