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Article

Functional analysis of potassium channels in Kv7.2 G271V mutant causing early onset familial epilepsy.

Brain research - 7 Aug 2015

Wang Juanjuan, Li Yuan, Hui Zhiyan, Cao Min, Shi Ruiming, Zhang Wei, Geng Limeng, Zhou Xihui

Abstract excerpt

Kv7 (KCNQ) channels underlying a class of voltage-gated K+ current are best known for regulating neuronal excitability. The first glycine (G) residue in the pore helix of Kv7.2 (KCNQ2) subunit is highly conserved among different classes of Kv7 channel family. A missense mutation causing the repla...

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Source

Identifiers

PMID: 25960349
DOI: 10.1016/j.brainres.2015.04.060

Genes

KCNQ2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-25960349-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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