Article
Identification of quantitative trait loci for murine autoimmune pancreatitis.
Journal of medical genetics - 1 Aug 2011
Asghari Farahnaz, Fitzner Brit, Holzhüter Stephanie-Anna, Nizze Horst, de Castro Marques Andreia, Müller Susen, Möller Steffen, Ibrahim Saleh M, Jaster Robert
Abstract excerpt
BACKGROUND AND AIMS: Autoimmune pancreatitis (AIP) represents a rare but clinically relevant cause of pancreatic inflammation. Using MRL/Mp mice as a model of spontaneous AIP, the genetic basis of the disease was studied. METHODS: To identify quantitative trait loci (QTL) of AIP, an advanced intercross line was studied, originating from MRL/MpJ parental mice and the following three mouse strains: Cast (healthy...
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