Article
In Silico Prediction of Human Leukocytes Antigen (HLA) Class II Binding Hepatitis B Virus (HBV) Peptides in Botswana.
Viruses - 6 Jul 2020
Choga Wonderful Tatenda, Anderson Motswedi, Zumbika Edward, Phinius Bonolo B, Mbangiwa Tshepiso, Bhebhe Lynnette N, Baruti Kabo, Kimathi Peter Opiyo, Seatla Kaelo K, Musonda Rosemary M, Bell Trevor Graham, Moyo Sikhulile, Blackard Jason T, Gaseitsiwe Simani
Abstract excerpt
Hepatitis B virus (HBV) is the primary cause of liver-related malignancies worldwide, and there is no effective cure for chronic HBV infection (CHB) currently. Strong immunological responses induced by T cells are associated with HBV clearance during acute infection; however, the repertoire of epitopes (epi) presented by major histocompatibility complexes (MHCs) to elicit these responses in various African...
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