Article
Identification of most frequent HLA class I antigen specificities in Botswana: relevance for HIV vaccine design.
Human immunology - 1 Feb 2001
Novitsky V, Flores-Villanueva P O, Chigwedere P, Gaolekwe S, Bussman H, Sebetso G, Marlink R, Yunis E J, Essex M
Abstract excerpt
Since the mid-1990s, southern African countries have been experiencing an expansion of human immunodeficiency virus type 1 (HIV-1) infection caused by HIV-1 subtype C. To facilitate the design of an HLA-based HIV vaccine, we studied the distribution of the HLA class I antigen specificities in Botswana, a southern African country with a high prevalence of HIV infection. Botswana's highly efficient health care...
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